The purpose of the study was to explore the relationship between job stress and job satisfaction for college amd university teachers in Taiwan.  Contents of research were separated as testing of hypothese and construction of a model.  The population was referenced 92 college and university school year from Ministry of Education in Taiwan, and sampling frame came form the items of “levels of school” under http://tw.yahoo.com. This study adopted stratified random sampling with experience indication of 4% as repoted, and selected 10,000 samples, and the resonded sample was 396.  The results shown that job stress had statistically negative influence on job satisfaction, teachers’ background had statistically negative influence on job stress, and teachers’ duty had statistically positive influence on job stress.  Except tested the relationship between job stress, and job satisfaction, the results of model 2 had some new discovery and may be developed as new theory, in considering the importance of teachers’ background and teachers’ duty beforehand.