This study tried to integrate resent researches on revised goal theory and approach-avoidance theory and the purposes were to (a) explore the effects of junior high school students’ mastery/approach performance goals and approach performance/avoidance performance goals on cognition, motivation, affect and learning behavior, (b) analyze the changes of students’ cognition, motivation, affect and learning behavior with the overall main effect of time, and (c) investigate the interactive effects of multiple goals by measuring time on junior high school students’ cognition, motivation, affect and learning behavior. Data were collected over half a year from 310 seventh grade students. The instruments used in this study included: Goal Orientations Scale, Cognitive Strategies Inventory, Motivation Inventory, Affect Inventory, and Learning Behavior Inventory. The statistical methods used to analyze the data were 4（multiple goals）×2（measuring time）two-way mixed design ANCOVA. The results indicated that (a) there were differences between mastery/approach performance goals’ and approach performance/avoidance performance goals’ students on using information-processing strategy, metacognitive strategy, ability belief, expectancy for success, positive effect, negative effect, self-handicapping and effort, (b) the development trends had a significant decline in junior high school students’ metacognitive strategy, ability belief, expectancy for success and effort over time but there was a significant increase of developmental trend in students’ self-handicapping and executive help-seeking over time; and (c) mastery/approach performance goals by measuring time had a significant interactive effects on students’ metacognitive strategy and task value, and approach performance/avoidance performance goals by measuring time had a significant interactive effects on students’ information-processing strategy, ability belief, task value and self-handicapping. Implications of the results and suggestions for school personnel and further research were also proposed.