Creative teaching is one of the effective ways to achieve the learning goals. If we could extract the critical factors from creative teaching process, we may offer support to teachers who desire to develop their creative teaching in a more effective way. Therefore, the main purpose of the current study is to explore the factors of creative science teaching and to improve teachers´ creative teaching ability. A structured Delphi questionnaire was developed based on the interviews of nine creative science-teachers and analysis of creative science-teaching programs (Lin & Liu, 2013). A two-round Delphi questionnaire survey was conducted to collect opinions from 14 scholars and teachers of science education to explore the factors of creative science teaching. Results indicated that among all the 22 creative science teaching factors, 6 factors were regarded as the most important: connect teaching to daily life, transform abstract to concrete, adopt cross-discipline/themes, use multiple assessments, use inquiry-based learning, as well as foster the ability of observing, independent thinking independently, and problem-solving. The results can be employed as guidelines and tools for teachers who desire to develop their own creative teaching programs in their careers.